Absolutely no, cause my height is 165cm U can take it and drive it well.
Maybe at ur first drive, u will yell "WOW!!! it is so wide and huge But after one month later u will drive it like march. The above is my experience
The most important thing is when u come out of ur Panamera, others look u as a little GIANT not a driver. The Benz S and Bmw 7 will give u a driver-look even u dress well and formal.